Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.
Vaso-occlusive crisis in Sickle cell disease might alter myocardial function through micro vascular obstruction.
1 France site
> 18 Years
The purpose of this study is to evaluate the efficacy, safety and tolerability of treatment with EDIT-301 in adult subjects with severe sickle cell disease (SCD).
12 United States sites
2 Canada sites
18 Years - 50 Years
Phase 1/Phase 2
Sickle cell anemia (SCA) is one of the most neglected diseases worldwide, according to the World Health Organization.
1 Brazil site
18 Years - 60 Years
Not Applicable
This clinical trial studies the effect of pre-transplant immunosuppression (PTIS) and donor stem cell transplant in treating patients with severe blood diseases (hemoglobinopathies).
1 United States site
2 Years - 30 Years
Early Phase 1
The overall purpose of this proposed study is to improve management of vaso-occlusive episodes (VOEs) in adult EDs.
8 United States sites
18 Years - 45 Years
Hb SS, Hb SC
Not Applicable
Sickle cell disease (SCD) is an inherited blood disorder.
1 France site
> 18 Years
This is a single-arm, mechanistic clinical trial to measure predictors of senescence and the in vivo survival of transfused red blood cells (RBCs) in individuals with sickle cell disease (SCD) receiving chronic transfusion therapy (CTT).
3 United States sites
> 6 Years
HbSS
Phase 1
The investigators are conducting a comparative effectiveness trial among adult patients with sickle cell disease (SCD) who report chronic pain (N = 350), randomized to receive either mobile phone-delivered computerized cognitive behavioral therapy (cCBT; n = 175) or digital education (m-Education; n = 175).
6 United States sites
> 18 Years
Not Applicable
The objective of this project is to determine the prevalence of hypertension, hyperlipidemia and hyperglycemia in the pediatric population with sickle cell disease who are obese in Mississippi compared to those pediatric patients with sickle cell disease who are not overweight/obese.
1 United States site
10 Years - 19 Years
HbSS, HbSC
This study assesses if using the medication desmopressin will decrease nightime bedwetting in children with sickle cell disease.
1 United States site
8 Years - 21 Years
Hemoglobin SS
Phase 4
