Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.
The purpose of this study is to evaluate the efficacy, safety and tolerability of treatment with EDIT-301 in adult subjects with severe sickle cell disease (SCD).
5 United States sites
18 to 50 Years
Phase 1/Phase 2
Vaso-occlusive crisis in Sickle cell disease might alter myocardial function through micro vascular obstruction.
1 France site
> 18 Years
This clinical trial studies the effect of pre-transplant immunosuppression (PTIS) and donor stem cell transplant in treating patients with severe blood diseases (hemoglobinopathies).
1 United States site
2 to 30 Years
Early Phase 1
Sickle cell anemia (SCA) is one of the most neglected diseases worldwide, according to the World Health Organization.
1 Brazil site
18 to 60 Years
N/A
Worldwide, an estimated 200,000 babies are born with Sickle Cell Anemia (SCA) annually.
1 Uganda site
3 to 9 Years
Sickle Cell Anaemia, SCA
Phase 3
The investigators will attempt to develop a more accurate equation to estimate eGFR in pediatric and adult sickle cell patients .
4 United States sites
5 to 50 Years
SCA, HbSS
This study is being done to test a transplant method that may have fewer side effects (or less toxic, less harmful) than conventional high dose chemotherapy conditioning-based transplants for children and young adults with Sickle Cell Disease (SCD).
1 United States site
2 to 25 Years
Phase 2
Pain is the primary complication of sickle cell disease (SCD), including vaso-occlusive crises and more persistent, chronic pain.
1 United States site
8 to 17 Years
HbSS, HbSC
N/A
Background: Sickle cell disease (SCD) is a disorder that causes episodes of acute pain and progressive organ damage.
1 United States site
18 to 70 Years
HbSS
Phase 1/Phase 2
Background: Venous thromboembolism (VTE) includes the abnormal clotting of blood in a deep vein of the upper or lower limbs (deep vein thrombosis) that may travel to and block a blood vessel in the lung (pulmonary embolism).
1 United States site
18 to 80 Years
HbSS, HbSC, HbAS
